Investigation of the Formation Process of Two Piracetam Cocrystals during Grinding

• Main Authors: Keith Gordon (Author), Thomas Rades (Author), Claudia S. Leopold (Author), Clare J. Strachan (Author), Marten Klukkert (Author), Albrecht Sakmann (Author), Korbinian A. M. Löbmann (Author), Sönke Rehder (Author)
• Format: Book
• Published: MDPI AG, 2011-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cocrystal formation rates during dry grinding and liquid-assisted grinding were investigated by X-ray powder diffractometry and Raman spectroscopy. Two polymorphic forms of piracetam were used to prepare known piracetam cocrystals as model substances, i.e.,piracetam-citric acid and piracetam-tartari...