Novel Luteolin-Loaded Chitosan Decorated Nanoparticles for Brain-Targeting Delivery in a Sporadic Alzheimer's Disease Mouse Model: Focus on Antioxidant, Anti-Inflammatory, and Amyloidogenic Pathways

• 主要な著者: Haidy Abbas (著者), Nesrine S El Sayed (著者), Nancy Abdel Hamid Abou Youssef (著者), Passent M. E. Gaafar (著者), Mohamed R. Mousa (著者), Ahmed M. Fayez (著者), Manal A Elsheikh (著者)
• フォーマット: 図書
• 出版事項: MDPI AG, 2022-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Preparation and evaluation of a non-invasive intranasal luteolin delivery for the management of cognitive dysfunction in Alzheimer's disease (AD) using novel chitosan decorated nanoparticles. Development of luteolin-loaded chitosomes was followed by full in vitro characterization. In vivo effic...