New Insights into the Potential Roles of 3-Iodothyronamine (T1AM) and Newly Developed Thyronamine-Like TAAR1 Agonists in Neuroprotection

• Main Authors: Lorenza Bellusci (Author), Annunziatina Laurino (Author), Martina Sabatini (Author), Simona Sestito (Author), Paola Lenzi (Author), Laura Raimondi (Author), Simona Rapposelli (Author), Francesca Biagioni (Author), Francesco Fornai (Author), Alessandra Salvetti (Author), Leonardo Rossi (Author), Riccardo Zucchi (Author), Grazia Chiellini (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

3-Iodothyronamine (T1AM) is an endogenous high-affinity ligand of the trace amine-associated receptor 1 (TAAR1), detected in mammals in many organs, including the brain. Recent evidence indicates that pharmacological TAAR1 activation may offer a novel therapeutic option for the treatment of a wide r...