Antigen physiochemical properties allosterically effect the IgG Fc-region and Fc neonatal receptor affinity

The neonatal Fc receptor (FcRn) is a key membrane protein that plays an integral role in serum immunoglobulin (IgG) recycling, which extends the half-life of antibody. In addition, FcRn is known to traffic antigen-bound immunoglobulins (Ag-IgGs), and to interact with immune complexes to facilitate t...

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Main Authors: Yue Sun (Author), Alberto Estevez (Author), Tilman Schlothauer (Author), Aaron T. Wecksler (Author)
Format: Book
Published: Taylor & Francis Group, 2020-01-01T00:00:00Z.
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3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available