The voltage-sensing domain of kv7.2 channels as a molecular target for epilepsy-causing mutations and anticonvulsants

• 主要な著者: Francesco eMiceli (著者), MariaVirginia eSoldovieri (著者), Fabio Arturo Iannotti (著者), Vincenzo eBarrese (著者), Paolo eAmbrosino (著者), Maria eMartire (著者), Maria Roberta Cilio (著者), Maurizio eTaglialatela (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2011-02-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Understanding the molecular mechanisms underlying voltage-dependent gating in voltage-gated ion channels (VGICs) has been a major effort over the last decades. In recent years, changes in the gating process have emerged as common denominators for several genetically-determined channelopathies affect...