Potentiation of Morphine Analgesia by Adjuvant Activation of 5-HT7 Receptors

• Asıl Yazarlar: Alex Brenchat (Yazar), Miriam Ejarque (Yazar), Daniel Zamanillo (Yazar), José Miguel Vela (Yazar), Luz Romero (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2011-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Abstract.: Spinal blockade of 5-HT7 receptors has been reported to inhibit the antinociceptive effect of opioids. In this study, we found that subcutaneous administration of the selective 5-HT7 receptor agonist E-55888 (10 mg/kg) or the antagonist SB-258719 (5 mg/kg) exerted no effect on the tail-fl...