Febrile temperatures increase in vitro antibody affinity for malarial and dengue antigens.

• Main Authors: Razvan C Stan (Author), Katia S Françoso (Author), Rubens P S Alves (Author), Luís Carlos S Ferreira (Author), Irene S Soares (Author), Maristela M de Camargo (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Fever is a regulated increase of the body temperature resulting from both infectious and non-infectious causes. Fever is known to play a role in modulating immune responses to infection, but the potential of febrile temperatures in regulating antigen binding affinity to antibodies has not been explo...