Vemurafenib Inhibits Enterovirus A71 Genome Replication and Virus Assembly

• Main Authors: Bodan Hu (Author), Kenn Ka-Heng Chik (Author), Jasper Fuk-Woo Chan (Author), Jian-Piao Cai (Author), Hehe Cao (Author), Jessica Oi-Ling Tsang (Author), Zijiao Zou (Author), Yin-Po Hung (Author), Kaiming Tang (Author), Lilong Jia (Author), Cuiting Luo (Author), Feifei Yin (Author), Zi-Wei Ye (Author), Hin Chu (Author), Man-Lung Yeung (Author), Shuofeng Yuan (Author)
• Format: Book
• Published: MDPI AG, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Enterovirus A71 (EV-A71) infection is a major cause of hand, foot, and mouth disease (HFMD), which may be occasionally associated with severe neurological complications. There is currently a lack of treatment options for EV-A71 infection. The Raf-MEK-ERK signaling pathway, in addition to its critica...