Trypanosoma cruzi-specific IFN-γ-producing cells in chronic Chagas disease associate with a functional IL-7/IL-7R axis.

Trypanosoma cruzi-specific IFN-γ-producing cells in chronic Chagas disease associate with a functional IL-7/IL-7R axis.

<h4>Background</h4>The severity of cardiac disease in chronic Chagas disease patients is associated with different features of T-cell exhaustion. Here, we assessed whether the ability of T cells to secrete IFN-γ in response to T. cruzi was linked to disruption in immune homeostasis and i...

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Main Authors: María A Natale (Author), Gonzalo Cesar (Author), María G Alvarez (Author), Melisa D Castro Eiro (Author), Bruno Lococo (Author), Graciela Bertocchi (Author), María C Albareda (Author), Susana A Laucella (Author)
Format: Book
Published: Public Library of Science (PLoS), 2018-12-01T00:00:00Z.
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