HDAC inhibitors improve CRISPR-Cas9 mediated prime editing and base editing

Recent advances in CRISPR-Cas9 techniques, especially the discovery of base and prime editing, have significantly improved our ability to make precise changes in the genome. We hypothesized that modulating certain endogenous pathway cells could improve the action of those editing tools in mammalian...

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Main Authors: Nan Liu (Author), Lifang Zhou (Author), Guifeng Lin (Author), Yun Hu (Author), Yaoge Jiao (Author), Yanhong Wang (Author), Jingming Liu (Author), Shengyong Yang (Author), Shaohua Yao (Author)
Format: Book
Published: Elsevier, 2022-09-01T00:00:00Z.
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