Identifying genetic markers enriched by brain imaging endophenotypes in Alzheimer's disease

• Main Authors: Mansu Kim (Author), Ruiming Wu (Author), Xiaohui Yao (Author), Andrew J. Saykin (Author), Jason H. Moore (Author), Li Shen (Author), for the Alzheimer's Disease Neuroimaging Initiative (Author)
• Format: Book
• Published: BMC, 2022-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Alzheimer's disease (AD) is a complex neurodegenerative disorder and the most common type of dementia. AD is characterized by a decline of cognitive function and brain atrophy, and is highly heritable with estimated heritability ranging from 60 to 80 $$\%$$ % . The most stra...