Differentiated HASTR/ci35 cells: A promising in vitro human astrocyte model for facilitating CNS drug development studies

• Main Authors: Keita Kitamura (Author), Ryo Ito (Author), Kenta Umehara (Author), Hanae Morio (Author), Kosuke Saito (Author), Shota Suzuki (Author), Mari Hashimoto (Author), Yoshiro Saito (Author), Naohiko Anzai (Author), Hidetaka Akita (Author), Kan Chiba (Author), Tomomi Furihata (Author)
• Format: Book
• Published: Elsevier, 2018-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Astrocytes have shown longstanding promise as therapeutic targets for various central nervous system diseases. To facilitate drug development targeting astrocytes, we have recently developed a new conditionally immortalized human astrocyte cell line, termed HASTR/ci35 cells. In this study, in order...