Inhibition of MAPK and STAT3-SOCS3 by Sakuranetin Attenuated Chronic Allergic Airway Inflammation in Mice

• Main Authors: Fernanda P. R. Santana (Author), Rafael C. da Silva (Author), Simone dos S. Grecco (Author), Aruanã J. M. C. R. Pinheiro (Author), Luciana C. Caperuto (Author), Fernanda M. Arantes-Costa (Author), Samuel R. Claudio (Author), Kelly Yoshizaki (Author), Mariângela Macchione (Author), Daniel A. Ribeiro (Author), Iolanda F. L. C. Tibério (Author), Lídio G. Lima-Neto (Author), João H. G. Lago (Author), Carla M. Prado (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Asthma allergic disease is caused by airway chronic inflammation. Some intracellular signaling pathways, such as MAPK and STAT3-SOCS3, are involved in the control of airway inflammation in asthma. The flavonoid sakuranetin demonstrated an anti-inflammatory effect in different asthma models. Our aim...