Validation of a high-throughput and robust technique: BACs-on-beads assay (KaryoLite BoBs) for pre-implantation aneuploidy screening

• Hauptverfasser: Grace Wing Shan Kong (VerfasserIn), Yanlin Ma (VerfasserIn), Jian Ou (VerfasserIn), Yvonne Ka Yin Kwok (VerfasserIn), Wei Wang (VerfasserIn), Queenie Sum Yee Yeung (VerfasserIn), Cherry Kit Man Wong (VerfasserIn), Qi Li (VerfasserIn), Wen Xu (VerfasserIn), Weiying Lu (VerfasserIn), Hong Li (VerfasserIn), Tin Chiu Li (VerfasserIn), Kwong Wai Choy (VerfasserIn)
• Format: Buch
• Veröffentlicht: Elsevier, 2017-08-01T00:00:00Z.
• Schlagworte: article
• Online-Zugang: Connect to this object online.

Objective: This study aims to validate the BACs-on-Beads (BoB) technology as a robust and high throughput method for pre-implantation genetic screening (PGS) for aneuploidy. Material and methods: The performances with respect to the sensitivity, specificity, success rate and detection rate of this t...