LDHA-induced histone lactylation mediates the development of osteoarthritis through regulating the transcription activity of TPI1 gene

Osteoarthritis (OA) is a worldwide joint disease, leading to the physical pain, stiffness, and even disability. Lactate dehydrogenase A (LDHA) is known as a lactylation mediator that can regulate histone lactylation of its target genes. However, the role of LDHA-mediated histone H3 lysine 18 lactyla...

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Main Authors: Junfeng Xia (Author), Zongrui Qiao (Author), Xiao Hao (Author), Yin Zhang (Author)
Format: Book
Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
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3rd Floor Main Library

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