Beneficial Action of 2,4,4-Trimethyl-3-(15-hydroxypentadecyl)-2-cyclohexen-1-one, a Novel Long-Chain Fatty Alcohol, on Diabetic Hypoalgesia and Neuropathic Hyperalgesia

• Main Authors: Yutaka Tamura (Author), Mayuko Monden (Author), Hiroto Suzuki (Author), Masashi Yamada (Author), Keizo Koyama (Author), Hirohito Shiomi (Author)
• Format: Book
• Published: Elsevier, 2006-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The effects of 2,4,4-trimethyl-3-(15-hydroxypentadecyl)-2-cyclohexen-1-one (tCFA15) on diabetic hypoalgesia and neuropathic hyperalgesia were examined. Treatments of streptozotocin (STZ)-pretreated mice with tCFA15 (8 - 40 mg/kg, i.p.) for 7 days significantly reversed the depressed inflammatory noc...