Targeting the epidermal growth factor receptor (EGFR/ErbB) for the potential treatment of renal pathologies

• Main Authors: Mohamed Tawengi (Author), Yazan Al-Dali (Author), Abdelaziz Tawengi (Author), Ibrahim F. Benter (Author), Saghir Akhtar (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Epidermal growth factor receptor (EGFR), which is referred to as ErbB1/HER1, is the prototype of the EGFR family of receptor tyrosine kinases which also comprises ErbB2 (Neu, HER2), ErbB3 (HER3), and ErbB4 (HER4). EGFR, along with other ErbBs, is expressed in the kidney tubules and is physiologicall...