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A point mutation in the Pdia6 gene results in loss of pancreatic β-cell identity causing overt diabetes

Objective: Protein disulfide isomerases (PDIs) are oxidoreductases that are involved in catalyzing the formation and rearrangement of disulfide bonds during protein folding. One of the PDI members is the PDI-associated 6 (PDIA6) protein, which has been shown to play a vital role in β-cell dysfunctio...

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Main Authors: Nirav Florian Chhabra (Author), Anna-Lena Amend (Author), Aimée Bastidas-Ponce (Author), Sibylle Sabrautzki (Author), Marta Tarquis-Medina (Author), Stephan Sachs (Author), Marina Rubey (Author), Bettina Lorenz-Depiereux (Author), Annette Feuchtinger (Author), Mostafa Bakhti (Author), Heiko Lickert (Author), Gerhard K.H. Przemeck (Author), Martin Hrabě de Angelis (Author)
Format: Book
Published: Elsevier, 2021-12-01T00:00:00Z.
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