Exosome-mediated inhibition of microRNA-449a promotes the amplification of mouse retinal progenitor cells and enhances their transplantation in retinal degeneration mouse models

• Auteurs principaux: Chen Jun Guo (Auteur), Xiu Li Cao (Auteur), Yu Fei Zhang (Auteur), Kang Yi Yue (Auteur), Jing Han (Auteur), Hong Yan (Auteur), Hua Han (Auteur), Min Hua Zheng (Auteur)
• Format: Livre
• Publié: Elsevier, 2023-03-01T00:00:00Z.
• Sujets: article
• Accès en ligne: Connect to this object online.

Inherited and age-related retinal degenerations are the commonest causes of blindness without effective treatments. Retinal progenitor cells (RPCs), which have the multipotency to differentiate into various retinal cell types, are regarded as a promising source of cell transplantation therapy for re...