Exosome-mediated inhibition of microRNA-449a promotes the amplification of mouse retinal progenitor cells and enhances their transplantation in retinal degeneration mouse models

• Main Authors: Chen Jun Guo (Author), Xiu Li Cao (Author), Yu Fei Zhang (Author), Kang Yi Yue (Author), Jing Han (Author), Hong Yan (Author), Hua Han (Author), Min Hua Zheng (Author)
• Format: Book
• Published: Elsevier, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inherited and age-related retinal degenerations are the commonest causes of blindness without effective treatments. Retinal progenitor cells (RPCs), which have the multipotency to differentiate into various retinal cell types, are regarded as a promising source of cell transplantation therapy for re...