Proteomic analysis of excretory-secretory products of Heligmosomoides polygyrus assessed with next-generation sequencing transcriptomic information.

• Main Authors: Yovany Moreno (Author), Pierre-Paul Gros (Author), Mifong Tam (Author), Mariela Segura (Author), Rajesh Valanparambil (Author), Timothy G Geary (Author), Mary M Stevenson (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The murine parasite Heligmosomoides polygyrus is a convenient experimental model to study immune responses and pathology associated with gastrointestinal nematode infections. The excretory-secretory products (ESP) produced by this parasite have potent immunomodulatory activity, but the protein(s) re...