Regulation of lymphatic function and injury by nitrosative stress in obese mice

• Main Authors: Sonia Rehal (Author), Raghu P. Kataru (Author), Geoffrey E. Hespe (Author), Jung Eun Baik (Author), Hyeung Ju Park (Author), Catherine Ly (Author), JinYeon Shin (Author), Babak J. Mehrara (Author)
• Format: Book
• Published: Elsevier, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective: Obesity results in lymphatic dysfunction, but the cellular mechanisms that mediate this effect remain largely unknown. Previous studies in obese mice have shown that inducible nitric oxide synthase-expressing (iNOS+) inflammatory cells accumulate around lymphatic vessels. In the current s...