Betulin Alleviates the Inflammatory Response in Mouse Chondrocytes and Ameliorates Osteoarthritis via AKT/Nrf2/HO-1/NF-κB Axis

• Main Authors: Chenghao Ren (Author), Jie Jin (Author), Wei Hu (Author), Qi Chen (Author), Jian Yang (Author), Yaosen Wu (Author), Yifei Zhou (Author), Liaojun Sun (Author), Weiyang Gao (Author), Xiaolei Zhang (Author), Naifeng Tian (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Osteoarthritis (OA) is a common degenerative joint disease featuring the degeneration, destruction, and ossification of cartilage. Inflammation which may facilitate OA occurrence and development is considered as the main pathological factor. Betulin, a natural product extracted from birch bark, has...