Theoretical study on the design of allosteric inhibitors of diabetes associated protein PTP1B

The protein tyrosine phosphatase 1B (PTP1B) is a critical therapeutic target for type 2 diabetes mellitus (T2DM). Many PTP1B inhibitors have been reported, however, most of them lack high specificity and have adverse effects. Designing effective PTP1B inhibitors requires understanding the molecular...

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Main Authors: Jiuyu Zhan (Author), Zhenyang Liu (Author), Hongwei Gao (Author)
Format: Book
Published: Frontiers Media S.A., 2024-08-01T00:00:00Z.
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3rd Floor Main Library

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