New antituberculosis drugs: from clinical trial to programmatic use

• Main Authors: Gina Gualano (Author), Susanna Capone (Author), Alberto Matteelli (Author), Fabrizio Palmieri (Author)
• Format: Book
• Published: MDPI AG, 2016-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Treatment of multidrug-resistant tuberculosis (MDR-TB) cases is challenging because it relies on second-line drugs that are less potent and more toxic than those used in the clinical management of drug-susceptible TB. Moreover, treatment outcomes for MDR-TB are generally poor compared to drug sensit...