Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/HO-1 and NF-kB signaling by curcumin in streptozotocin-induced diabetic spinal cord central neuropathy

Suppression of neuronal apoptosis and glial activation with modulation of Nrf2/HO-1 and NF-kB signaling by curcumin in streptozotocin-induced diabetic spinal cord central neuropathy

IntroductionDiabetes is a global disease, commonly complicated by neuropathy. The spinal cord reacts to diabetes by neuronal apoptosis, microglial activation, and astrocytosis, with a disturbance in neuronal and glial Nuclear factor erythroid 2-related factor/Heme oxygenase-1 (Nrf2/HO-1) and Nuclear...

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Main Authors: Hassan Reda Hassan Elsayed (Author), Mohammed R. Rabei (Author), Mohamed Mahmoud Abdelraheem Elshaer (Author), Eman Mohamad El Nashar (Author), Mansour Abdullah Alghamdi (Author), Zainah Al-Qahtani (Author), Ahmed Nabawy (Author)
Format: Book
Published: Frontiers Media S.A., 2023-03-01T00:00:00Z.
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