A PDX1-ATF transcriptional complex governs β cell survival during stress
Objective: Loss of insulin secretion due to failure or death of the insulin secreting β cells is the central cause of diabetes. The cellular response to stress (endoplasmic reticulum (ER), oxidative, inflammatory) is essential to sustain normal β cell function and survival. Pancreatic and duodenal h...
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Elsevier,
2018-11-01T00:00:00Z.
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