CDK9 as a Valuable Target in Cancer: From Natural Compounds Inhibitors to Current Treatment in Pediatric Soft Tissue Sarcomas

• Main Authors: Matteo Cassandri (Author), Rossella Fioravanti (Author), Silvia Pomella (Author), Sergio Valente (Author), Dante Rotili (Author), Giada Del Baldo (Author), Biagio De Angelis (Author), Rossella Rota (Author), Antonello Mai (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cyclin-Dependent Kinases (CDKs) are well-known reliable targets for cancer treatment being often deregulated. Among them, since the transcription-associated CDK9 represents the sentry of cell transcriptional homeostasis, it can be a valuable target for managing cancers in which the transcriptional m...