Fragmentomics of plasma mitochondrial and nuclear DNA inform prognosis in COVID-19 patients with critical symptoms

• Main Authors: Haiqiang Zhang (Author), Lingguo Li (Author), Yuxue Luo (Author), Fang Zheng (Author), Yan Zhang (Author), Rong Xie (Author), Rijing Ou (Author), Yilin Chen (Author), Yu Lin (Author), Yeqin Wang (Author), Yan Jin (Author), Jinjin Xu (Author), Ye Tao (Author), Ruokai Qu (Author), Wenwen Zhou (Author), Yong Bai (Author), Fanjun Cheng (Author), Xin Jin (Author)
• Format: Book
• Published: BMC, 2024-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background The mortality rate of COVID-19 patients with critical symptoms is reported to be 40.5%. Early identification of patients with poor progression in the critical cohort is essential to timely clinical intervention and reduction of mortality. Although older age, chronic diseases, hav...