The TRPV4 Agonist GSK1016790A Regulates the Membrane Expression of TRPV4 Channels

• Main Authors: Sara Baratchi (Author), Peter Keov (Author), William G. Darby (Author), Austin Lai (Author), Khashayar Khoshmanesh (Author), Peter Thurgood (Author), Parisa Vahidi (Author), Karin Ejendal (Author), Peter McIntyre (Author)
• Format: Book
• Published: Frontiers Media S.A., 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

TRPV4 is a non-selective cation channel that tunes the function of different tissues including the vascular endothelium, lung, chondrocytes, and neurons. GSK1016790A is the selective and potent agonist of TRPV4 and a pharmacological tool that is used to study the TRPV4 physiological function in vitr...