Impaired remodeling phase of fracture repair in the absence of matrix metalloproteinase-2

• Main Authors: Shirley Lieu (Author), Erik Hansen (Author), Russell Dedini (Author), Danielle Behonick (Author), Zena Werb (Author), Theodore Miclau (Author), Ralph Marcucio (Author), Céline Colnot (Author)
• Format: Book
• Published: The Company of Biologists, 2011-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

SUMMARY The matrix metalloproteinase (MMP) family of extracellular proteases performs crucial roles in development and repair of the skeleton owing to their ability to remodel the extracellular matrix (ECM) and release bioactive molecules. Most MMP-null skeletal phenotypes that have been previously...