Protective role of down-regulated microRNA-31 on intestinal barrier dysfunction through inhibition of NF-κB/HIF-1α pathway by binding to HMOX1 in rats with sepsis

Abstract Background Intestinal barrier dysfunction is a significant clinical problem, commonly developing in a variety of acute or chronic pathological conditions. Herein, we evaluate the effect of microRNA-31 (miR-31) on intestinal barrier dysfunction through NF-κB/HIF-1α pathway by targeting HMOX1...

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Main Authors: Cheng-Ye Zhan (Author), Di Chen (Author), Jin-Long Luo (Author), Ying-Hua Shi (Author), You-Ping Zhang (Author)
Format: Book
Published: BMC, 2018-10-01T00:00:00Z.
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