Mechanism of Action of Natural Compounds in Peripheral Multiorgan Dysfunction and Hippocampal Neuroinflammation Induced by Sepsis

• Main Authors: Ramona D'Amico (Author), Mario Tomasello (Author), Daniela Impellizzeri (Author), Marika Cordaro (Author), Rosalba Siracusa (Author), Livia Interdonato (Author), Ali Saber Abdelhameed (Author), Roberta Fusco (Author), Vittorio Calabrese (Author), Salvatore Cuzzocrea (Author), Rosanna Di Paola (Author)
• Format: Book
• Published: MDPI AG, 2023-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Bacterial sepsis induces the production of excessive pro-inflammatory cytokines and oxidative stress, resulting in tissue injury and hyperinflammation. Patients recovering from sepsis have increased rates of central nervous system (CNS) morbidities, which are linked to long-term cognitive impairment...