Degradation of ribosomal and chaperone proteins is attenuated during the differentiation of replicatively aged C2C12 myoblasts

Abstract Background Cell assays are important for investigating the mechanisms of ageing, including losses in protein homeostasis and 'proteostasis collapse'. We used novel isotopic labelling and proteomic methods to investigate protein turnover in replicatively aged (>140 population do...

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Main Authors: Alexander D. Brown (Author), Claire E. Stewart (Author), Jatin G. Burniston (Author)
Format: Book
Published: Wiley, 2022-10-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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