Loss of Ovarian Function Results in Increased Loss of Skeletal Muscle in Arthritic Rats

• Main Authors: Roberto Furlanetto Júnior (Author), Fernanda Maria Martins (Author), Anselmo Alves de Oliveira (Author), Paulo Ricardo Prado Nunes (Author), Márcia Antoniazi Michelin (Author), Eddie Fernando Candido Murta (Author), Fábio Lera Orsatti (Author)
• Format: Book
• Published: Federação Brasileira das Sociedades de Ginecologia e Obstetrícia, 2016-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective We studied the effects of loss of ovarian function (ovariectomy) onmuscle mass of gastrocnemius and themRNA levels of IGF-1, atrogin-1, MuRF-1, andmyostatin in an experimental model of rheumatoid arthritis in rats. Methods We randomly allocated 24 female Wistar rats (9 weeks, 195.3±17.4 gr...