Early uptake and continuous accumulation of thallium-201 chloride in a benign mixed tumor of soft tissue: Case Report
<p>Abstract</p> <p>A case of benign mixed tumor of the soft tissue in a 64-year-old Japanese male is presented. He noticed a painless, elastic hard mass sized 3 cm in the right knee, which gradually grew larger and harder in the last 5 years. Magnetic resonance imaging demonstrated...
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2010-05-01T00:00:00Z.
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LEADER | 00000 am a22000003u 4500 | ||
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001 | doaj_d33df9fb31d84c3c823f60be6712b24b | ||
042 | |a dc | ||
100 | 1 | 0 | |a Hamada Kenichiro |e author |
700 | 1 | 0 | |a Outani Hidetatsu |e author |
700 | 1 | 0 | |a Yoshizawa Hidenori |e author |
700 | 1 | 0 | |a Kubo Chiaki |e author |
700 | 1 | 0 | |a Yuki Michiko |e author |
700 | 1 | 0 | |a Tomoeda Miki |e author |
700 | 1 | 0 | |a Song Misa |e author |
700 | 1 | 0 | |a Iizuka Norishige |e author |
700 | 1 | 0 | |a Kitamura Masanori |e author |
700 | 1 | 0 | |a Yoshizato Katsuhiko |e author |
700 | 1 | 0 | |a Jin Yu-Fen |e author |
700 | 1 | 0 | |a Nagata Shigenori |e author |
700 | 1 | 0 | |a Araki Nobuhito |e author |
700 | 1 | 0 | |a Funauchi Masahiro |e author |
700 | 1 | 0 | |a Tomita Yasuhiko |e author |
245 | 0 | 0 | |a Early uptake and continuous accumulation of thallium-201 chloride in a benign mixed tumor of soft tissue: Case Report |
260 | |b BMC, |c 2010-05-01T00:00:00Z. | ||
500 | |a 10.1186/1746-1596-5-34 | ||
500 | |a 1746-1596 | ||
520 | |a <p>Abstract</p> <p>A case of benign mixed tumor of the soft tissue in a 64-year-old Japanese male is presented. He noticed a painless, elastic hard mass sized 3 cm in the right knee, which gradually grew larger and harder in the last 5 years. Magnetic resonance imaging demonstrated a mass lesion embedded in the subcutaneous tissue with low and high signal intensity at T1- and T2-weighted images, respectively. Tl-201 scintigraphy showed an early uptake of Tl-201 within the lesion at 10 minutes after injection, which was slightly decreased but still continued at 2 hours later. The patient underwent a resection of tumor, and the pathological diagnosis was a benign mixed tumor of soft tissue without high vascularity, characterized by histological features similar to pleomorphic adenomas in the salivary glands. Immunohistochemical study proved expression of Na<sup>+</sup>/K<sup>+</sup>-ATPase of tumor cells. Overexpression of Na<sup>+</sup>/K<sup>+</sup>-ATPase of the tumor might be responsible for the early uptake of Tl-201, and poor vascular structure in this tumor might lead to continuous accumulation. The Tl-201 scintigraphic features of mixed tumor of soft tissue are assessed to resemble those of malignant soft tissue tumors.</p> | ||
546 | |a EN | ||
690 | |a Pathology | ||
690 | |a RB1-214 | ||
655 | 7 | |a article |2 local | |
786 | 0 | |n Diagnostic Pathology, Vol 5, Iss 1, p 34 (2010) | |
787 | 0 | |n http://www.diagnosticpathology.org/content/5/1/34 | |
787 | 0 | |n https://doaj.org/toc/1746-1596 | |
856 | 4 | 1 | |u https://doaj.org/article/d33df9fb31d84c3c823f60be6712b24b |z Connect to this object online. |