Early uptake and continuous accumulation of thallium-201 chloride in a benign mixed tumor of soft tissue: Case Report

<p>Abstract</p> <p>A case of benign mixed tumor of the soft tissue in a 64-year-old Japanese male is presented. He noticed a painless, elastic hard mass sized 3 cm in the right knee, which gradually grew larger and harder in the last 5 years. Magnetic resonance imaging demonstrated...

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Main Authors: Hamada Kenichiro (Author), Outani Hidetatsu (Author), Yoshizawa Hidenori (Author), Kubo Chiaki (Author), Yuki Michiko (Author), Tomoeda Miki (Author), Song Misa (Author), Iizuka Norishige (Author), Kitamura Masanori (Author), Yoshizato Katsuhiko (Author), Jin Yu-Fen (Author), Nagata Shigenori (Author), Araki Nobuhito (Author), Funauchi Masahiro (Author), Tomita Yasuhiko (Author)
Format: Book
Published: BMC, 2010-05-01T00:00:00Z.
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042 |a dc 
100 1 0 |a Hamada Kenichiro  |e author 
700 1 0 |a Outani Hidetatsu  |e author 
700 1 0 |a Yoshizawa Hidenori  |e author 
700 1 0 |a Kubo Chiaki  |e author 
700 1 0 |a Yuki Michiko  |e author 
700 1 0 |a Tomoeda Miki  |e author 
700 1 0 |a Song Misa  |e author 
700 1 0 |a Iizuka Norishige  |e author 
700 1 0 |a Kitamura Masanori  |e author 
700 1 0 |a Yoshizato Katsuhiko  |e author 
700 1 0 |a Jin Yu-Fen  |e author 
700 1 0 |a Nagata Shigenori  |e author 
700 1 0 |a Araki Nobuhito  |e author 
700 1 0 |a Funauchi Masahiro  |e author 
700 1 0 |a Tomita Yasuhiko  |e author 
245 0 0 |a Early uptake and continuous accumulation of thallium-201 chloride in a benign mixed tumor of soft tissue: Case Report 
260 |b BMC,   |c 2010-05-01T00:00:00Z. 
500 |a 10.1186/1746-1596-5-34 
500 |a 1746-1596 
520 |a <p>Abstract</p> <p>A case of benign mixed tumor of the soft tissue in a 64-year-old Japanese male is presented. He noticed a painless, elastic hard mass sized 3 cm in the right knee, which gradually grew larger and harder in the last 5 years. Magnetic resonance imaging demonstrated a mass lesion embedded in the subcutaneous tissue with low and high signal intensity at T1- and T2-weighted images, respectively. Tl-201 scintigraphy showed an early uptake of Tl-201 within the lesion at 10 minutes after injection, which was slightly decreased but still continued at 2 hours later. The patient underwent a resection of tumor, and the pathological diagnosis was a benign mixed tumor of soft tissue without high vascularity, characterized by histological features similar to pleomorphic adenomas in the salivary glands. Immunohistochemical study proved expression of Na<sup>+</sup>/K<sup>+</sup>-ATPase of tumor cells. Overexpression of Na<sup>+</sup>/K<sup>+</sup>-ATPase of the tumor might be responsible for the early uptake of Tl-201, and poor vascular structure in this tumor might lead to continuous accumulation. The Tl-201 scintigraphic features of mixed tumor of soft tissue are assessed to resemble those of malignant soft tissue tumors.</p> 
546 |a EN 
690 |a Pathology 
690 |a RB1-214 
655 7 |a article  |2 local 
786 0 |n Diagnostic Pathology, Vol 5, Iss 1, p 34 (2010) 
787 0 |n http://www.diagnosticpathology.org/content/5/1/34 
787 0 |n https://doaj.org/toc/1746-1596 
856 4 1 |u https://doaj.org/article/d33df9fb31d84c3c823f60be6712b24b  |z Connect to this object online.