Studies on the formation and forming mechanism of the related substance E in potassium clavulanate production by HPLC-MS/MS

• Main Authors: Chuanqing Zhong (Author), Guangxiang Cao (Author), Xiaoqing Jin (Author), Fengshan Wang (Author)
• פורמט: ספר
• יצא לאור: Universidade de São Paulo, 2014-04-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

The objective of this study was to investigate the formation and forming mechanism of the related substance E in potassium clavulanate production. The impurity with retention time of 11.1 min in potassium clavulanate final product was confirmed as the related substance E by high performance liquid c...