Design considerations in a sib-pair study of linkage for susceptibility loci in cancer

• Main Authors: Finkelstein Dianne M (Author), Yeap Beow Y (Author), Amos Christopher I (Author), Kerber Richard A (Author), Thomas Duncan C (Author)
• Format: Book
• Published: BMC, 2008-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

<p>Abstract</p> <p>Background</p> <p>Modern approaches to identifying new genes associated with disease allow very fine analysis of associaton and can be performed in population based case-control studies. However, the sibpair design is still valuable because it require...