Coinfection with Leishmania major and Staphylococcus aureus enhances the pathologic responses to both microbes through a pathway involving IL-17A.

• Main Authors: Tiffany Y Borbón (Author), Breanna M Scorza (Author), Gwendolyn M Clay (Author), Fellipe Lima Nobre de Queiroz (Author), Alan J Sariol (Author), Jayden L Bowen (Author), Yani Chen (Author), Bayan Zhanbolat (Author), Corey P Parlet (Author), Diogo G Valadares (Author), Suzanne L Cassel (Author), William M Nauseef (Author), Alexander R Horswill (Author), Fayyaz S Sutterwala (Author), Mary E Wilson (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2019-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cutaneous leishmaniasis (CL) is a parasitic disease causing chronic, ulcerating skin lesions. Most humans infected with the causative Leishmania protozoa are asymptomatic. Leishmania spp. are usually introduced by sand flies into the dermis of mammalian hosts in the presence of bacteria from either...