Efficacy and safety of low-dose versus high-dose hydrocortisone to treat hypotension in neonates: a protocol for a systematic review and meta-analysis

• Main Authors: Samira Samiee-Zafarghandy (Author), Kristi Watterberg (Author), Jacques Lacroix (Author), John van den Anker (Author), Abdul Razak (Author), Katelyn Sushko (Author), Catherine Litalien (Author), Nada Al-Rawahi (Author)
• Format: Book
• Published: BMJ Publishing Group, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background Impaired adrenal function is a well-described entity in critically ill term and preterm neonates with systemic hypotension. The standard treatment for neonatal hypotension includes volume expanders and vasopressors. Recent evidence supports the use of glucocorticoids for the primary or re...