Abrogation of mercuric chloride-induced nephritis in the Brown Norway rat by treatment with antibodies against TNFα

• Autori principali: A. Molina (Autore), F. Sánchez-Madrid (Autore), T. Bricio (Autore), A. Martín (Autore), E. Escudero (Autore), V. Alvarez (Autore), F. Mampaso (Autore)
• Natura: Libro
• Pubblicazione: Hindawi Limited, 1995-01-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

HgCl2 induces an autoimmune disease in the Brown Norway rat characterized by synthesis of autoantibodies (mainly, anti-GBM Abs), severe proteinuria and interstitial nephritis. Also, HgCl2- injected rats develop glomerular cell infiltrates consisting of ED1+ cells (monocyte/macrophage), starting on d...