Abrogation of mercuric chloride-induced nephritis in the Brown Norway rat by treatment with antibodies against TNFα
HgCl2 induces an autoimmune disease in the Brown Norway rat characterized by synthesis of autoantibodies (mainly, anti-GBM Abs), severe proteinuria and interstitial nephritis. Also, HgCl2- injected rats develop glomerular cell infiltrates consisting of ED1+ cells (monocyte/macrophage), starting on d...
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Hindawi Limited,
1995-01-01T00:00:00Z.
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