Prostate cancer cells and exosomes in acidic condition show increased carbonic anhydrase IX expression and activity

• मुख्य लेखकों: Mariantonia Logozzi (लेखक), Clemente Capasso (लेखक), Rossella Di Raimo (लेखक), Sonia Del Prete (लेखक), Davide Mizzoni (लेखक), Mario Falchi (लेखक), Claudiu T. Supuran (लेखक), Stefano Fais (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Taylor & Francis Group, 2019-01-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Acidity and hypoxia are crucial phenotypes of tumour microenvironment both contributing to the selection of malignant cells under a micro evolutionistic pressure. During the tumour progression, nanovesicles, called exosomes and the metalloenzyme carbonic anhydrase IX (CA IX) affect the tumour growth...