Immunomodulatory Effect of Proteasome Inhibitors via the Induction of Immunogenic Cell Death in Myeloma Cells

• Main Authors: Maiko Matsushita (Author), Sho Kashiwazaki (Author), Satoshi Kamiko (Author), Michio Kobori (Author), Makoto Osada (Author), Hisako Kunieda (Author), Maki Hirao (Author), Daiju Ichikawa (Author), Yutaka Hattori (Author)
• Format: Book
• Published: MDPI AG, 2023-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Several anti-cancer drugs are known to have immunomodulatory effects, including immunogenic cell death (ICD) of cancer cells. ICD is a form of apoptosis which is caused by the release of damage-associated molecular patterns (DAMPs), the uptake of cancer antigens by dendritic cells, and the activatio...