Synthesis and Cytotoxic Activity of Combretastatin A-4 and 2,3-Diphenyl-2<i>H</i>-indazole Hybrids

• Main Authors: Jaime Pérez-Villanueva (Author), Félix Matadamas-Martínez (Author), Lilián Yépez-Mulia (Author), Vadim Pérez-Koldenkova (Author), Martha Leyte-Lugo (Author), Karen Rodríguez-Villar (Author), Francisco Cortés-Benítez (Author), Ana Perla Macías-Jiménez (Author), Ignacio González-Sánchez (Author), Ariana Romero-Velásquez (Author), Juan Francisco Palacios-Espinosa (Author), Olivia Soria-Arteche (Author)
• Format: Book
• Published: MDPI AG, 2021-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Cancer is the second leading cause of death, after cardiovascular diseases. Different strategies have been developed to treat cancer; however, chemotherapy with cytotoxic agents is still the most widely used treatment approach. Nevertheless, drug resistance to available chemotherapeutic agents is st...