Evaluation of qPCR-based assays for leprosy diagnosis directly in clinical specimens.

• Main Authors: Alejandra Nóbrega Martinez (Author), Marcelo Ribeiro-Alves (Author), Euzenir Nunes Sarno (Author), Milton Ozório Moraes (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The increased reliability and efficiency of the quantitative polymerase chain reaction (qPCR) makes it a promising tool for performing large-scale screening for infectious disease among high-risk individuals. To date, no study has evaluated the specificity and sensitivity of different qPCR assays fo...