High Throughput Screening Identifies Novel Lead Compounds with Activity against Larval, Juvenile and Adult Schistosoma mansoni.

• Main Authors: Nuha R Mansour (Author), Ross Paveley (Author), J Mark F Gardner (Author), Andrew S Bell (Author), Tanya Parkinson (Author), Quentin Bickle (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

An estimated 600 million people are affected by the helminth disease schistosomiasis caused by parasites of the genus Schistosoma. There is currently only one drug recommended for treating schistosomiasis, praziquantel (PZQ), which is effective against adult worms but not against the juvenile stage....