Elaphuri Davidiani Cornu Improves Depressive-Like Behavior in Mice and Increases Neurotrophic Factor Expression in Mouse Primary Astrocytes via cAMP and ERK-Dependent Pathways

• Main Authors: Yue Zhu (Author), Mengqiu Liu (Author), Suchen Qu (Author), Cheng Cao (Author), Chongqi Wei (Author), Xue-er Meng (Author), Qianyin Lou (Author), Dawei Qian (Author), Jin-ao Duan (Author), Yuhua Ding (Author), Zhengxiang Han (Author), Ming Zhao (Author)
• Format: Book
• Published: Frontiers Media S.A., 2020-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Elaphuri Davidiani Cornu (EDC) is the natural shedding horn of Elaphurus davidiauus Millne-Edwards that was used by people in ancient China for maintaining physical and mental health. We evaluated the antidepressant effect of EDC using depression-like animal models and explored possible mechanisms i...