Pharmacokinetics and tolerability of apremilast in healthy Korean adult men

• Main Authors: Ki Young Huh (Author), Yewon Choi (Author), Jim Nissel (Author), Maria Palmisano (Author), Xiaomin Wang (Author), Liangang Liu (Author), Francisco Ramirez‐Valle (Author), Howard Lee (Author)
• Format: Book
• Published: Wiley, 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract We performed a two‐part study to evaluate the pharmacokinetics, safety, and tolerability of oral apremilast, a phosphodiesterase 4 inhibitor indicated for the treatment of psoriasis, in healthy Korean adult men. In part 1, there were 12 subjects who randomly received a single oral dose of a...