Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart

Evaluation of Tumor-Targeting Properties of an Antagonistic Bombesin Analogue RM26 Conjugated with a Non-Residualizing Radioiodine Label Comparison with a Radiometal-Labelled Counterpart

Radiolabelled antagonistic bombesin analogues are successfully used for targeting of gastrin-releasing peptide receptors (GRPR) that are overexpressed in prostate cancer. Internalization of antagonistic bombesin analogues is slow. We hypothesized that the use of a non-residualizing radioiodine label...

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Main Authors: Maryam Oroujeni (Author), Ayman Abouzayed (Author), Fanny Lundmark (Author), Bogdan Mitran (Author), Anna Orlova (Author), Vladimir Tolmachev (Author), Ulrika Rosenström (Author)
Format: Book
Published: MDPI AG, 2019-08-01T00:00:00Z.
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