Anti-Alzheimer Activity of Combinations of Cocoa with Vinpocetine or Other Nutraceuticals in Rat Model: Modulation of Wnt3/β-Catenin/GSK-3β/Nrf2/HO-1 and PERK/CHOP/Bcl-2 Pathways

• Main Authors: Karema Abu-Elfotuh (Author), Amina M. A. Tolba (Author), Furqan H. Hussein (Author), Ahmed M. E. Hamdan (Author), Mohamed A. Rabeh (Author), Saad A. Alshahri (Author), Azza A. Ali (Author), Sarah M. Mosaad (Author), Nihal A. Mahmoud (Author), Magdy Y. Elsaeed (Author), Ranya M. Abdelglil (Author), Rehab R. El-Awady (Author), Eman Reda M. Galal (Author), Mona M. Kamal (Author), Ahmed M. M. Elsisi (Author), Alshaymaa Darwish (Author), Ayah M. H. Gowifel (Author), Yasmen F. Mahran (Author)
• Format: Book
• Published: MDPI AG, 2023-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Alzheimer's disease (AD) is a devastating illness with limited therapeutic interventions. The aim of this study is to investigate the pathophysiological mechanisms underlying AD and explore the potential neuroprotective effects of cocoa, either alone or in combination with other nutraceuticals,...